Background: Gingivitis can develop as a reaction to dental plaque. It can be limited by curtailing plaque build-up\nthrough actions including tooth brushing and the use of medicinal mouthwashes, such as those containing\nchlorhexidine digluconate (CHX), that can reach parts of the mouth that may be missed when brushing. This study\naimed to compare dental stain control of twice-daily brushing with a sodium fluoride (NaF) dentifrice containing\n67 % sodium bicarbonate (NaHCO3) or a commercially available NaF silica dentifrice without NaHCO3, while using a\nmouthwash containing 0.2 % CHX.\nMethods: This was a 6-week, randomised, two-site, examiner-blind, parallel-group study in healthy subjects with at\nleast ââ?¬Ë?mildââ?¬â?¢ stain levels on the facial surfaces of ââ?°Â¥4 teeth and ââ?°Â¥15 bleeding sites. Assessment was via modified\nLobene Stain Index (MLSI), the score being the mean of stain intensity multiplied by area (MLSI [IxA]).\nResults: One hundred and fifty of 160 randomised subjects completed the study. There were no significant differences\nin Overall (facial and lingual) MLSI (IxA) scores between dentifrices. The Facial MLSI (IxA) was statistically significant\nat 6 weeks, favouring the 67 % NaHCO3 dentifrice (p = 0.0404). Post-hoc analysis, conducted due to a significant site\ninteraction, found significant differences for all MLSI scores in favour of the 67 % NaHCO3 dentifrice at Site 1 (both\nweeks) but not Site 2.\nConclusions: No overall significant differences were found between a 67 and 0 % NaHCO3 dentifrice in controlling\nCHX stain; a significant difference on facial surfaces suggests advantage of the former on more accessible surfaces.
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